M350 X16:16 Y16 Z16:16:16:16 E16 I1 ; configure microstepping with interpolation M92 X80.00:80.00 Y80.00 Z1600.00:1600.00:1600.00:1600.00 E420.00 ; set steps per mm M566 X900.00:900.00 Y900.00 Z60.00:60.00:60.00:60.00 E120.00 ; set maximum instantaneous speed changes (mm/min) M203 X6000.00:6000.00 Y6000.00 Z180.00:180.00:180.00:180.00 E1200.00 ; set maximum speeds (mm/min) M201 X500.00:500.00 Y500.00 Z20.00:20.00:20.00:20.00 E250.00 ; set accelerations (mm/s^2) M906 X800:800 Y800 Z900:900:900:900 E800 ; set motor currents (mA)

should be

M350 X16 Y16 Z16 E16 I1 ; configure microstepping with interpolation M92 X80.00 Y80.00 Z1600.00 E420.00 ; set steps per mm M566 X900.00 Y900.00 Z60.00 E120.00 ; set maximum instantaneous speed changes (mm/min) M203 X6000.00 Y6000.00 Z180.00 E1200.00 ; set maximum speeds (mm/min) M201 X500.00 Y500.00 Z20.00 E250.00 ; set accelerations (mm/s^2) M906 X800 Y800 Z900 E800 ; set motor currents (mA)

Only the extruders need to be independently defined for each motor because each extruder is an independent axis. Multiple motors on an axis only get the values per axis.

@OsherHachm said in help setting z axis 4 motors and endstop and one probe:

The new problem I'm having is when I homing the X axis it's run slowly and the Z axis as well at the same time(hapooening only for the X axis).

I'm not really sure what you mean by this.

@OsherHachm said in help setting z axis 4 motors and endstop and one probe:

I'm leveling the nuzzle from the low end ( z min is close to the bed) so I decided for every axis will be one end stop.

I'm not sure what you mean by this either. Your endstops are configured at the high end of the Z axis. Are they actually located at the low end?

If you're using the probe to level, does your bed.g work correctly?

Also, if it's an IR probe, you don't need M401 and M402 in your bed.g