Duet Mini 5+ with 4x extruders and 4x axis

I have a 4x axis and 4x extruder 3D printer and I’m working with the Duet 3 Mini 5+ with the 2x addon card (total 7 on mini 5).
My question is if 3x extruders are from the main board with the 2x add on. Then have the 4th extruder using CAN. Will this work or should all 4x extruders be the same (not mixing with CAN).?
If so, was thinking of moving my 2x Z axis to CAN then.
Thanks!
`mike 
You can spread the extruders over multiple CAN boards. The Z motors are best left connected to the main board, due to limitations when a Z probe is used.

@dc42 Thanks!
just to verify before I order.
Keeping like type motors, to like type drivers is best.for Z1,Z2,x,y =Duet3 mini5+,
for E0e1e2e3 = 1xDUET 3 TOOL DISTRIBUTION BOARD and 4x DUET 3 TOOLBOARD 1LCcorrect?
thanks!
`mike