I experience something similar to that on my IDEX configuration. Steps to reproduce this problem: (all steps done via web interface)
Step 1: Home All
Step 2: Select Tool 1 (U axis)
Step 3: Move Y axis 100 mm in positive direction
Step 4: Move U axis 15 (or any value) in negative direction
Step 5: Move Y axis 1 mm in positive direction
When step 5 is performed Y axis supposed to move 1mm but the U axis moves back to the home position unintentionally instead.