I just realised: you said you want to use external drivers, but you also said you have a DueX5. That means you will face the same issue on the expansion header: the 5 EN/CS pins on the expansion header are used as CS pins for the TMC2660 drivers on the DueX5.
If you need to use a DueX board to support additional heaters or fans, and you also want to use 3 external drivers, you should use a DueX2 board instead.
You can also connect 2 external drivers to the CONN_SD connector.
Bear in mind that the built-in TMC2660 drivers support higher currents than other 3D printer control boards, so they can drive some types of Nema23 motor directly.