@miguelh18 said in 3.6V differential signals on duet2 WIFI or Duex5:

Last question: is the Duex2 jumper removal necessary for using both DueX5 and expansion breakout board? I would like to use Drives 5-7 on the DueX5, and Drives 8,9 on the expansion board.

No it's not necessary; however the driver status reported for drivers 8,9 won't be meaningful, and the enable signals for drivers 8.9 on the breakout board won't work. If you want to use those enable signals, connect the breakout board to the EXP1/EXP2 connectors instead.