Perhaps you can go through this guide to get things going.
https://duet3d.dozuki.com/Guide/Ender+3+Pro+and+Duet+Maestro+Guide+Part+2:+Configuration/38
and
https://duet3d.dozuki.com/Guide/Ender+3+Pro+and+Duet+Maestro+Guide+Part+3:+Commissioning/39
The CR10-S5 and the Ender 3 are fairly similar in many ways. If you go through the process in the configurator and change the settings as needed you should end up with a good starting config. You can even get the answers to most of your questions from the M3D config files.
Those two guides should help you at least get connected to the Maestro through the Web Control.